El rol de los fármacos antiinflamatorios en la depresión

  • Julio Torales Universidad Nacional de Asunción
  • Israel González Universidad Nacional de Asunción
  • Iván Barrios Universidad Nacional de Asunción
Palabras clave: trastorno depresivo mayor; depresión; antiinflamatorios


Existen varias teorías con respecto a la patogénesis de la depresión. Actualmente se encuentra en investigación la teoría inflamatoria, con resultados que sugieren una relación de la depresión a la inflamación, de la inflamación a la depresión o, quizá con más precisión, una relación bidireccional entre estas dos entidades.

En este artículo se presenta brevemente una descripción del trastorno depresivo mayor con sus criterios diagnósticos y datos epidemiológicos, una explicación de la teoría inflamatoria de la depresión y una actualización acerca de la evidencia con respecto al uso de fármacos antiinflamatorios como parte del abordaje terapéutico de esta patología.


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